About 80% to 90% of the time, UTIs are caused by E. coli bacteria introduced to your urinary tract
UTI-causing E. coli may be introduced to your body from the food you eat, namely chicken, as well as pork and beef
One study suggested E. coli from food may cause 640,000 UTIs in the U.S. each year, and numbers may be higher in areas near concentrated animal feeding operations (CAFOs)
If not effectively treated, UTIs can progress to kidney infections and sepsis; deaths from UTIs increased by 2.4-fold from 1990 to 2019
Methylene blue is a highly effective agent against UTIs, as it kills virtually any pathogen in your bladder without disrupting the microbiome the way antibiotics do
Common signs of a UTI:
Burning with urination
Frequent urges to urinate
Lower abdominal pain or aching
Blood in your urine (sometimes, but not always)
Cloudy or foul-smelling urine.
If the infection spreads to your kidneys, you may experience additional signs of illness, including:
Fatigue
Fever, chills or night sweats
Pain in your side, back or groin
Mental changes or confusion
Nausea and vomiting
In older adults, confusion, delirium, dizziness and other behavioral changes may be the only signs of a UTI.
As for treatment, consider methylene blue, the parent molecule for hydroxychloroquine and chloroquine, off-patent drugs commonly used to treat not only malaria but also COVID-19. Methylene blue is actually the oldest drug in the world. It was founded in 1876 and used as a textile dye for blue jeans, but it has many important medicinal benefits.
It is a highly effective agent against UTIs, as it’s excreted by your kidneys into your bladder where it reaches very high concentrations and becomes a potent oxidant stress that kills virtually any pathogen there — without disrupting the microbiome the way antibiotics do. Plus, it has the additional “side effect” of improving brain health and reducing dementia, making it ideal for UTI treatment in older adults.
by JM MD
Sources and References:
Front Public Health. 2022; 10: 888205
The Washington Post January 9, 2024 (archived)
National Kidney Foundation, Urinary Tract Infections
Front Public Health. 2022; 10: 888205., Results
Journal of Molecular Biology April 17, 2019 [Epub ahead of print]
Disease-A-Month. The Etiology of Urinary Tract Infection. February 2003
CDC.gov E. coli Q&A
Wired July 11, 2012
mBio August 2018, 9 (4) e00470-18
Scientific Reports volume 10, Article number: 906 (2020)
Consumer Reports December 21, 2015
The New York Times March 27, 2023
One Health June 2023, Volume 16, 100518, Abstract
Front. Med., 18 June 2021
Penn Medicine, Urinary Tract Infection (UTI)
Cureus. 2022 Dec; 14(12): e32321
Cochrane Library, April 17, 2023
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